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what does equivocal mean in a blood test hsv

The FDA has granted Emergency Use Authorizations for COVID-19 vaccines that have been shown to be safe and effective as established by data from large clinical trials. Blood testing means looking for antibodies. Allina Health [Internet]. Can a herpes test return a false-positive or false-negative results? A Blood Test Used to Detect Genital Herpes Antibodies. The chance of passing it on while pregnant is low but if it happens it can lead to disabilities and death., Theres also a social stigma associated with this virus that can be damaging to yourmental health if you ever become infected.. For instance, the test is likely to be less accurate if the healthcare provider swabs the scab rather than the sore itself. This test looks to see if you have antibodies against either HSV-1 or HSV-2 the two kinds of herpes viruses., Your body begins to make two relevant types of HSV-1 antibody or HSV-2 antibody around 18 to 21 days after youre first infected. These cookies may also be used for advertising purposes by these third parties. All results under 3.5 are suspect, and the closer to 1.0, the more likely the result is false. ), The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. By using this Site you agree to the following, By using this Site you agree to the following, The Best IOL for 2022 RXSight Light Adjusted Lens, Will refractive surgery such as LASIK keep me out of glasses all my life. This can happen with many kinds of diagnostic tests. What do you do? The study of antibody seropositivity in a population helps government officials understand the extent of infection and the cumulative incidence of infection. Here's what you need to know. Light-headedness and infection are rare but also possible. Infection with COVID-19 (2019 novel coronavirus, 2019-nCoV) causes respiratory problems in humans. These tipscan help. HSV antibodies are present even when there are no symptoms. Learn more about the link between genital herpes and HIV in this fact sheet. She said she I would have to have my blood tested again. The window period for genital herpes can range from three to 12 weeks. Your provider may ask you to lie on your back for an hour or two after the procedure. retailers. Synonyms of equivocal 1 a : subject to two or more interpretations and usually used to mislead or confuse an equivocal statement b : uncertain as an indication or sign equivocal evidence 2 a : of uncertain nature or classification equivocal shapes b : of uncertain disposition toward a person or thing : undecided an equivocal attitude c He adds that this is why using protection during sexual contact is so important, regardless of what blood tests say. A positive result from both tests can be considered a definitive diagnosis of herpes. Both the PCR test and antigen test can be used to determine whether you have been infected with the COVID-19 virus. These tests have limits. All the standard stuff was tested (i.e. Herpes Fast Facts; [cited 2018 Jun 13]; [about 2 screens]. All the standard stuff was tested (i.e. Specifically, it's a blood test. By contrast, a false-negative result is likely if your body has not produced enough antibodies to reach detectable levels. Elizabeth Boskey, PhD, MPH, CHES, is a social worker, adjunct lecturer, and expert writer in the field of sexually transmitted diseases. Health Information: Herpes Tests: Test Overview; [updated 2017 Mar 20; cited 2018 Jun 13]; [about 2 screens]. Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. This includes a PCR test that can detect the genetic material of the virus and a viral culture that can "grow" the virus in the lab. Faulty techniques or faulty testing kit. Available from: UW Health [Internet]. It may mean the sample didn't have enough of the virus to be detected. It looks for antibodies to herpes simplex virus 1 (HSV-1) and herpes simplex virus 2 (HSV-2). People with symptoms can have one or more blisters on or around the genitals, rectum, or mouth. They will also evaluate you for signs or symptoms of herpes to choose which tests to use. Clinical studies are ongoing for antiviral drugs like hydroxychloroquine, chloroquine remdesivir, lopinavir and favipiravir, as well as COVID-19 vaccines. But the herpes simplex virus antibodies test can help identify the recurrence of a previous infection. HSV-1 and HSV-2 have a few differences. But, other tests may be more useful and/or reliable in certain situations. This is because current herpes tests are not as exact as tests for chlamydia and gonorrhea. Ideally, patients should be quarantined at home or an institution for 2 weeks after the symptoms completely disappear. Different methods of testing have been launched to trace COVID-19 infection. If you want to reduce the severity and number of your outbreaks, your provider may prescribe a medicine that can help. Serologic screening for genital herpes: An updated evidence report and systematic review for the US Preventive Services Task Force. Your healthcare provider can examine you and order the appropriate tests. This article discusses the IgG blood test and how it can determine if you have herpes simplex virus (HSV). Mayo Foundation for Medical Education and Research; c19982018. What is the difference between HSV-1 and HSV-2? IgM antibodies are detectable after a few days, but they disappear within a few weeks. Not all hospitals have access to this method, however. You were right Dr. HHH as usual. Chlamydia and Gonorrhea: Screening. One big area of misunderstanding is blood testing and herpes infections. Equivocal: Your test results could not be interpreted as Positive or Negative. Negative; 0.90 IV or less; Equivocal; 0.91-1.09 IV; Positive; 1.10 IV or more; HSV-1 Test Results Interpretation Using IgG. diabetes, chronic respiratory disease, and cancer. Health Information: Herpes Tests: How It Is Done; [updated 2017 Mar 20; cited 2018 Jun 13]; [about 5 screens]. Shingles vs. It means that you need to repeat the test in the next four to six weeks again and meanwhile observe protection to avoid transmission. And, whether you have symptoms or not, know that you're not alone if you are herpes-positive. Call in advance for details and to confirm that they provide the IgG test. Available from: UW Health [Internet]. Although it can be uncomfortable, talking to a healthcare provider about your sexual history is the best way to know whether you should test for herpes and other STDs. Your provider may put a numbing cream on your back before this injection. The accuracy of all medical tests, including herpes tests, is measured based on two values: sensitivity and specificity. So just because a test shows that you have antibodies in your blood doesnt mean you dont need to be vaccinated. STI vs. STD: Key Differences and Resources for College Students, Serologic screening for genital herpes: An updated evidence report and systematic review for the US Preventive Services Task Force, Evaluation of commercial herpes simplex virus IgG and IgM enzyme immunoassays, Final Recommendation Statement: Human Immunodeficiency virus (HIV) Infection: Screening, HSV polymerase chain reaction (PCR), which can detect the genetic material (DNA) that makes up the herpes virus, Some human immunodeficiency virus (HIV) service organizations. This test does not indicate the site of HSV infection. All of this tells us that sure, there are some currently available blood tests for herpes that can tell you your status or give you some idea of it but they're still far from perfect. A test that is 90% sensitive will correctly identify 90 people out of 100 who have the disease. The results of your HSV blood test will generally be reported as either: If your test is equivocal, your healthcare provider might consider results of other tests you've had done to make your diagnosis. The sensitivity and specificity vary by the type of test used: The likelihood of a false-positive result is low but can occur due to user error or improper storage or handling. HSV-2 is the type that mainly causes genital herpes. Bulebird365 2 mo. Available from: UW Health [Internet]. Getting tested for COVID-19 can identify you as a positive or negative patient of the disease. Even if there is only a small amount of virus, the genetic material can be amplified enough to return an accurate positive diagnosis. While most cases can be detected by week three, some people may take far longer to produce detectable antibodies. Some may only offer free testing for: Search for free or low-cost STI clinics in your area by using the GetTested locator offered by the CDC. If this blood test is positive, but you do not have any known genital herpes outbreaks, did not have a positive culture test, and did not have a positive PCR result, then an immunoblot test may be necessary to confirm a diagnosis. What Does a Positive Herpes IgM Test Result Mean? There is very little risk to having a blood test. "Let's say they have a blood test come in positive but theyve never had a lesion. Read our, Sensitivity and Specificity in Medical Testing. A "negative" viral . Sometimes herpes can be spread even if there are no visible sores. Virol J. (Less is known about low-positive HSV-1 results than about HSV-2, so it is harder to be certain. Positive antibody test results mean that: A positive antibody test result does not mean you are immune to COVID-19. An equivocal COVID-19 antibody test result means that the result could not be interpreted as positive or negative, Understanding COVID-19 antibody test results. Gon, Chlamydia, Hep, HIV, Syphilis, Herpes) from an online testing source. They can help you decide what is best for you based on your sexual and medical history. Are there risks to a COVID-19 antibody test? Aside from the two aforementioned blood tests, there are other FDA-approved gG-based blood tests that can offer accurate results, which the ASHA has broken down in this handy chart. Available from: National Heart, Lung, and Blood Institute [Internet]. Neither of you has ever experienced symptoms, so when the test comes back and reveals that you're herpes-positive, you're stunned. This means that a herpes test can say you have the virus when you do not actually have it. Thank you for taking the time to confirm your preferences. The most common reasons for equivocal results are presence of an immune response but unclear if against the infection being tested for (COVID-19 in this case) or similar infections (the common cold is a type of coronavirus). I had the same test for the hsv 1 and tested 4.67h and the range was 0-0.89. They can also take a sample or swab from a blister or sore that is not already crusted over or healing. They may also offer HIV testing, which is recommended once for all people ages 1565. People infected with COVID-19 can still be contagious even when they stop feeling sick, so precautionary measures should continue for at least 2 weeks after symptoms disappear and until the COVID-19 test result is negative. Equivocal: Results unclear If your test is equivocal, your healthcare provider might consider results of other tests you've had done to make your diagnosis. Have a great weekend and thanks again for all you do. It is not recommended as a general screening test for everyone. Antibodies against the spike protein can indicate how successful a. You should also check to see if they accept your insurance, if you're enrolled in a plan. Nothing. 5. You will be subject to the destination website's privacy policy when you follow the link. Madison (WI): University of Wisconsin Hospitals and Clinics Authority; c2018. 2016;316(23):2531-2543. doi:10.1001/jama.2016.17138, Liermann K, Schfler A, Henke A, and Sauerbrei A. Why do I need this test? The answers are available on any of a hundred or so other threads on this forum -- or start a new thread of your own. Herpes: oral: Overview; [updated 2018 Jun 13; cited 2018 Jun 13]; [about 2 screens]. Thank you, {{form.email}}, for signing up. Since a positive result means that your body has built an IgG immune response to HSV, a negative IgG test means that your body has never needed to do so and you have never been infected with HSV. for both hsv1&2 igm equivocal at .98 Doctor rounded it off to the positive side and gave me the herpes meds. HSV antibodies produced in response to these antigens help the immune system target its attack. The IgM test is still used by some doctors even though it has been denounced by the Centers for Disease Control and Prevention (CDC). The problem is that blood tests for herpes when no lesions or symptoms are present are often bullshit. Two blood tests are used to screen for herpes. When someone gets genital herpes, it can take up to 16 weeks or more after an exposure for the current tests to detect it. IgG results may be considered along with IgM results. To recap, while there are some tests for herpes that can prove correct, none are 100 percent perfect, and blood tests are particularly problematic since they can produce false positives and negatives. If you've been diagnosed with genital herpes, condom use can reduce your risk of spreading the infection to others. article. It can take three to six weeks from the initial infection before enough IgG is produced to be detected. Elizabeth Boskey, PhD, MPH, CHES, is a social worker, adjunct lecturer, and expert writer in the field of sexually transmitted diseases. A technician will take your blood sample and test for one or both kinds of antibodies: Because the antibody test is a simple blood test, it does not involve major health risks. They have a lab onsite and results are available in 10 minutes. Herpes can also be dangerous to a newborn baby. These cookies allow us to count visits and traffic sources so we can measure and improve the performance of our site. If you have clinical signs of an infection and your HSV IgG test is negative, repeat the test in about four to six weeks to confirm the results. Test results are ready within two to five working days. 2023 Dotdash Media, Inc. All rights reserved. Opioid Addiction Treatment Rates in U.S. Have Flatlined, Study Finds, Many American Teens Are in Mental Health Crisis: Report, Why People Love Selfies: It's Not About Vanity. I left work early, had a mental breakdown in the parking lot, and yes, think I almost had a stroke worrying about this. Another advantage of the IgG test is that it's more accurate when it comes to telling the difference between HSV-1 and HSV-2. The tube is sent to a lab for evaluation. The bump was painful. Ten people will have a false-negative result. There are two main types of HSV: HSV-1, which usually causes blisters or cold sores around the mouth (oral herpes) Should wear a mask or not? Equivocal (could not be interpreted as positive or negative). What Are the Symptoms of the Herpes Simplex Virus? For many, due to the high rate of stigma still surrounding herpes, it can mean feelings of self-contempt, humiliation, and distress, all of which could be avoided if you aren't experiencing any symptoms. Available from: Merck Manual Consumer Version [Internet]. The U.S. National Institutes of Health (NIH), National Institute of Allergy and Infectious Diseases (NIAID) supports research to develop prevention methods and treatments for genital herpes. From there, the two of you have blood tests and ask to be screened for STIs, including both types of herpes: herpes simplex virus type 1 (HSV-1), which most commonly causes oral herpes, and herpes . I should have remembered to say that in addition to Western blot, people with equivocal HerpeSelect HSV-2 results can have another commercial type-specific HSV antibody test, such as the BiokitUSA rapid test (which is what you had) or the Trinity Biotech Captia (R) test (in the US) or the Kalon HSV-2 test (in the UK and elsewhere). An IgG blood test is used to diagnose herpes simplex virus infection. When an ELISA is confirmed with a Western blot, it is unlikely for a herpes diagnosis to be wrong. Public clinics tend to be cheaper. You may have slight pain or bruising at the spot where the needle was put in, but most symptoms go away quickly. Could you have already had COVID-19 and not know it? Your test results should be ready within two to five working days. Can a herpes test give a false-positive result? You don't have HSV-2. what does it mean if a blood test for hsv 2 herpeselect with a blood count of .90 negative 0.90-1.10 equivocal 1.10 positive . The chances of wrong test results are higher for people who are at low risk of infection. According to the U.S. Preventive Services Task Force, the accuracy of the two blood used to diagnose herpes breaks down as follows: Due to its high level of sensitivity and specificity, the Western blot is considered the gold standard of herpes blood testing. All of this is to say that unless you have symptoms consistent with the herpes virus, why put yourself through the emotional turmoil of getting a blood test that may or may not give you legit results? What is the difference between HSV and HPV? By now, everyone knows about COVID-19. Herpes simplex virus type 1 (HSV-1) or herpes simplex virus type 2 (HSV-2) cause genital herpes. These two types of antibodies are called IgG and IgM antibodies., IgG antibodies are the most common kind and IgM antibodies are the first kind that your body makes when you first come into contact with a virus or bacteria. Available from: UF Health: University of Florida Health [Internet]. The COVID-19 antibody test, also known as a serology test, is a blood test that looks for antibodies to determine whether you have had a recent or past infection of the virus that causes COVID-19. Screening tests: a review with examples. As you knew oh so well--my Rapid test was negative for Type II. Typically, your first outbreak is the most severe. In most cases of infection with the herpes simplex virus, you wont have any symptoms at all or theyll be very mild. This is precisely why so many doctors, as well as the CDC, do not recommend getting tested unless you have the common symptoms associated with herpes, such as itching, burning, or a blister. Herpes: Whats the Difference? Negative antibody test results mean that: Negative antibody test results do not always indicate with certainty that you do not have or have not had an infection with SARS-CoV-2.Some people who are infected may never develop antibodies. Both tests rely on the direct detection of HSV using fluids obtained from a swab of a herpes sore. If you had a lumbar puncture, you may have pain or tenderness in your back where the needle was inserted. A polymerase chain reaction (PCR) test can detect HSV by making copies of the virus' genetic material in a process known as nucleic amplification. With an equivocal result, it is really not possible to know right now if you are making antibody due to a new infection or its not positive, period. The range was 0-0.89 I tested at .98h and the interperation was equivocal. A herpes antibodies test works by looking in your blood for HSV-1 antibodies or HSV-2 antibodies typically the IgG type but sometimes the IgM type. The minimum time period between contact with HSV and the production of detectable antibodies, what's called the window period, is four to six weeks after the suspected exposure. ago Ohh okay, thank you so much for the advice! Both rely on a swab of fluid from a herpes sore. If you still have symptoms of herpes, you may need to get tested again. This includes chlamydia and gonorrhea testing for sexually active women under age 25, women ages 25 and older, and men with certain risk factors. There is no known risk to having a swab test. Both of your values are suspect, though if I had to guess, I would guess that you are HSV 1 positive. Specifically, its a blood test that looks for certain antibodies in your body., Antibodies are proteins that are made by your immune system to fight off particular pathogens usually bacteria and viruses. Doctoral Degree. Bethesda (MD): U.S. Department of Health and Human Services; Blood Tests; [cited 2018 Jun 13]; [about 3 screens]. What drugs could help fight coronavirus COVID-19? Specificity, on the other hand, refers to a test's ability to correctly identify someone who doesn't have the disease. IgG is the type of antibody found in abundance in blood about 14 days after symptoms start. Take this COVID-19 prevention quiz to learn how to protect yourself. I Spent a Week at an $850-A-Night Postpartum Retreat, Once you get over the sticker shock, reality sets in: These are the amenities, Even Oprah Couldnt Get Her Doctors to Take Her Menopause Symptoms Seriously, In a conversation with Drew Barrymore and Maria Shriver, she said perimenopause is shrouded in stigma and shame.. Learn why anti-flu respiratory drugs and home remedies may prove useful to treat or prevent serious coronavirus infections. This waiting period is commonly known as the "window period. Yes, a herpes test can give a false-positive result. Now what? We take your privacy seriously. Your HSV 1 positive could be falsely triggering an HSV 2 equivocal test. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Antibodies are proteins produced by your bodys immune system to fight a particular virus after you have been infected or vaccinated. Parts of the IgG protein, like all antibodies, are made by the immune system to attack specific disease-causing organisms (pathogens), like viruses and bacteria. Take this quiz to find out! In other words, if you've been exposed to oral herpes (which most people have), results of the IgM test could lead you to believe you're positive for genital herpes, when in fact you simply have antibodies against HSV-1. All information these cookies collect is aggregated and therefore anonymous. Bring your insurance card (if applicable) and a method of payment. Breakouts typically happen in the genital region when you have HSV-2 and near your lips when you have HSV-1. Feltner C, Grodensky C, Ebel C, et al. What are the symptoms you should look for? HSV-1 is the type of herpes primarily associated with cold sores. Ten people will have a false-negative result. NIH also maintains a database with information aboutclinical trials around the world. The best way to prevent genital herpes or another STD is to not have sex. This may prevent you from getting a headache afterward. The Centers for Disease Control and Prevention (CDC) currently advises against HSV testing for people without symptoms. coronavirus (covid-19) health center/coronavirus a-z list/does equivocal mean positive? But don't assume that a free STI clinic will have the test or provide it free of charge. Terms of Use. For instance, ASHA says that while an IgG test can distinguish between HSV-1 and HSV-2, the problem is that the time it takes for IgG antibodies to reach a detectable level varies from person to person. It looks for antibodies to herpes simplex virus 1 (HSV-1) and herpes simplex virus 2 (HSV-2). Kenilworth (NJ): Merck & Co. Inc.; c2018. An HSV IgG test is typically used to confirm a genital herpes infection. The herpes virus was not found. I value your comments here even though I think I know what you are going to say.thanks so much again. Youre pregnant or trying to become pregnant. Shingles vs. To use the sharing features on this page, please enable JavaScript. Genital herpes: Overview; [updated 2018 Jun 13; cited 2018 Jun 13]; [about 2 screens]. 37,321 satisfied customers. A viral culture, on the other hand, will tell you which virus you have, though it takes some time to come back. To ensure that an initial positive result is correct, a second test using a different method of detection is used to confirm the results. MMWR Recomm Rep. 2021;70(4):1-187. doi:10.15585/mmwr.rr7004a1, McQuillan Q, Kruszon-Moran D, Flagg E, and Paulrose-Ram, R. Prevalence of herpes simplex virus type 1 and type 2 in persons aged 1449: united states, 20152016. More posts from r/Herpes 35K subscribers I realize that's a pretty strong word, but after speaking with doctors who have administered these tests, it's become more and more apparent to me how misunderstood and in some cases, just plain wrong the results they give are. The herpes simplex virus antibodies test is a blood test that screens for the herpes simplex virus (HSV). Vertebrae are the small backbones that make up your spine. PCR is considered the gold standard of testing in cases where herpes has invaded the brain or spinal cord (typically in people with advanced HIV infection). Determine if suspected vaccine-related adverse events were caused by vaccine-strain VZV. You can find out more about our use, change your default settings, and withdraw your consent at any time with effect for the future by visiting Cookies Settings, which can also be found in the footer of the site. According to the Centers for Disease Control and Prevention, HSV testing can be used in asymptomatic (symptom-free) people who: Herpes can be diagnosed with blood tests. Though antibodies are also present in saliva, salivary antibody tests may not work as well as blood tests. Sign up for our daily send to get the latest beauty news and product launches. The test will also determine which type of HSV virus you may have acquired. I was informed that anything 1.09 or above is positive; for genital herpes. Determine susceptibility to varicella. No one likes blisters or sores, but neither does anyone love having acne, a widespread condition (85 percent of young adults battle it) without the same level of attached shame. There are two blood tests used to diagnose herpes infections: The accuracy of the newer-generation herpes blood tests is exceptionally high. All rights reserved. This assay is based on glycoprotein G-2, purified from HSV-2 infected cells, and is specific for type 2 antibodies. World Health Organization (WHO). Sensitivity is how often a test correctly identifies someone with a disease. Went to another doctor who brushed it off an ingrown hair. Genital herpes is a common sexually transmitted infection (STI). 2014;199:29-34. doi:10.1016/j.jviromet.2014.01.001. You could have a current infection or have been recently infected. Your response is a HUGE relief. According to the American Sexual Health Association (ASHA), IgM tests can lead to deceptive results, as well as false assumptions about how and when a person acquired HSV. For example, some tests detect antibodies to the spike protein produced in response to viral infection or the vaccine. It may mean you have an active infection (you currently have sores), or were infected in the past (you have no sores). An equivocal test result means that the result could not be interpreted as positive or negative. Hopefully, you will still get this. The injection site is cleaned with an antiseptic swab. An antibody is a substance made by the body's immune system when it detects harmful substances such as the herpes virus. University of California, San Francisco. Rather, it detects the IgG antibodies, or immune proteins, that your body produces in response to the viral infection. Centers for Disease Control and Prevention (CDC). J Virol Methods. An equivocal test does not mean herpes if that was true then every patient with an equivocal test would always be positive which is jit the casenot the case. Herpes blood testing is a two-step process in which an initial positive result is followed by a second confirmatory test. For an ELISA to return an accurate result, the immune system needs to produce enough antibodies to reach detectable levels. Avoiding contact with infected people, social distancing, not touching your face, frequent hand washing, cleaning, and disinfecting of frequently touched surfaces can help to reduce your risk of contracting the 2019 novel coronavirus. There are about 491 million cases of HSV-2 worldwide or 13% of the global population between the ages of 15 and 49., HSV is spread through direct contact with the virus. If a patient has no blisters or sores, providers may use a blood test to see if they have herpes. From there, the two of you have blood tests and ask to be screened for STIs, including both types of herpes: herpes simplex virus type 1 (HSV-1), which most commonly causes oral herpes, and herpes simplex virus type 2 (HSV-2), which most commonly leads to genital herpes. They have a sensitivity level of 96% to 100% in detecting herpes. (they used LabCorp). Madison (WI): University of Wisconsin Hospitals and Clinics Authority; c2018. How Does the Herpes Antibodies Test Work? Cookies used to enable you to share pages and content that you find interesting on CDC.gov through third party social networking and other websites. An HSV viral culture is a process in which the virus is "grown" in the lab using a swab of fluid. The specimen probably will go to the Unviersity of Washington lab -- the place where the HSV WB test was developed, and the main lab that offers the service on a regular basis. Culturing a sample from an active outbreak of HSV is the best method to diagnose a current infection. Both HSV-1 and HSV-2 are recurring infections. Herpes testing is generally recommended for people with herpes symptoms only. If you think you have herpes because you have symptoms or suspect that you may have been exposed to the virus through sex, a healthcare provider can offer you a blood test to confirm whether you have been infected with the herpes simplex virus (HSV). An IgG blood test is used to diagnose herpes simplex virus (HSV) infection. Mayo Foundation for Medical Education and Research; c19982018. What to Do If You Get a Positive At-Home COVID-19 Test Result. They may choose tests based on several factors (e.g., number of sex partners, if you had an STI before, etc.). My apologies for any second guessing here. Available from: Merck Manual Consumer Version [Internet]. This can happen during sex or while giving birth., The virus leads to an increased risk of infection with human immunodeficiency virus (HIV). Learn more about laboratory tests, reference ranges, and understanding results.

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